![]() The stabilizing effect of NPPE and Chol were synergistic. ![]() Incorporation of NPPE into PC SUV decreases leakage in the presence of serum or phosphate-buffered saline, no strictly related to size increase observed and to the surface negative charge present. Either small unilamellar vesicles (SUV) or large unilamellar vesicles (LUV) were used. Liposomes containing negatively-charged phospholipid, N-palmitoylphosphatidylethanolamine (NPPE) were examined for stability in the presence of human serum, using the release of the entrapped 5,6-carboxyfluorescein as an aqueous marker.
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